Journal Club february 2021

Here you can find the list with the most interesting articles that were published in the paediatric literature of last month.


You may find the answer to the following questions:

  • How well do we perform paediatric procedural sedation and analgesia in A&E?
  • Why do not parents refuse Covid-19 vaccination?
  • Is surgery a good option in neutropenic appendicitis?
  • What are predictors of extubation failure and extremely preterm infants?
  • Is home phototherapy feasible for term neonates?
  • Is maternal caffeine intake during pregnancy related to food allergy in children?
  • Are maternal autoimmune diseases linked to ADHD?
  • What are the vestibular disorders in congenital CMV infection?
  • Are lower HbA1c targets associated with better metabolic control?


Selection of articles for the Pediatric Journal Club: FEBRUARY 2021




Global Ethical Considerations regarding Mandatory Vaccination in Children.

Savulescu J, et al. J Pediatr. 2021 Jan 20:S0022-3476(21)00028-7.


The Ethics of Predicting Autism Spectrum Disorder in Infancy.

MacDuffie KE, et al. J Am Acad Child Adolesc Psychiatry. 2021 Jan 19:S0890-8567(21)00018-6


Contemporary Management of Urinary Tract Infection in Children.

Mattoo TK, et al. Pediatrics. 2021 Jan 21:e2020012138.


Overview of nontuberculous mycobacterial disease in children.

Ford TJ, et al. J Paediatr Child Health. 2021 Jan;57(1):15-18.


Paediatric chemical burns: a clinical review.

Nguyen ATM, et al. Eur J Pediatr. 2021 Jan 6


Should children be vaccinated against COVID-19 now?

Wong BLH, et al. Arch Dis Child. 2021 Jan 5:archdischild-2020-321225.


Identification and Management of Eating Disorders in Children and Adolescents.

Hornberger LL, et al. Pediatrics. 2021 Jan;147(1):e2020040279




Maternal Education and Academic Achievement in Schoolchildren: The Role of Cardiorespiratory Fitness.

Reina-Gutiérrez S, et al. J Pediatr. 2021 Jan 27:S0022-3476(21)00081-0


Early Versus Late Brain Magnetic Resonance Imaging after Neonatal Hypoxic Ischemic Encephalopathy Treated with Therapeutic Hypothermia.

O’Kane A, et al. J Pediatr. 2021 Jan 27:S0022-3476(21)00084-6


Pediatric procedural sedation and analgesia in the emergency department: surveying the current European practice.

Sahyoun C, et al. Eur J Pediatr. 2021 Jan 28.


Early Motor Function of Children With Autism Spectrum Disorder: A Systematic Review.

Lim YH, et al. Pediatrics. 2021 Jan 28:e2020011270


Discharge Age and Weight for Very Preterm Infants: 2005-2018.

Edwards EM, et al. Pediatrics. 2021 Jan 28:e2020016006


Evaluation of COVID-19 Vaccine Refusal in Parents.

Yigit M, et al..Pediatr Infect Dis J. 2021 Jan 4;


Migraine and Tension-Type Headache Among Children and Adolescents: Application of International Headache Society Criteria in a Clinical Setting.

Genizi J, et al..J Child Neurol. 2021 Jan 28:883073820988417


Surgery as a Viable Option in Neutropenic Appendicitis.

Williams K, et al. Pediatrics. 2021 Jan 27:e2020035279.


Appendectomy Versus Observation for Appendicitis in Neutropenic Children With Cancer.

Many BT, et al. Pediatrics. 2021 Jan 27:e2020027797


No change in neurodevelopment at 11 years after extremely preterm birth.

Marlow N, et al. Arch Dis Child Fetal Neonatal Ed. 2021 Jan 27:fetalneonatal-2020-320650.


Viral co-infections among SARS-CoV-2-infected children and infected adult household contacts.

Pigny F, et al. Eur J Pediatr. 2021 Jan 27:1-5.


A matter of taste: Results of antibiotic suspension tasting among paediatric doctors.

Abbotsford J, et al. J Paediatr Child Health. 2021 Jan;57(1):161-162.


Effect of a Family Media Use Plan on Media Rule Engagement Among Adolescents: A Randomized Clinical Trial.

Moreno MA, et al. JAMA Pediatr. 2021 Jan 25.


Predictors and outcomes of extubation failure in extremely preterm infants.

Kidman AM, et al. J Paediatr Child Health. 2021 Jan 23.


The perfusion index histograms predict patent ductus arteriosus requiring treatment in preterm infants.

Osman AA, et al. Eur J Pediatr. 2021 Jan 24.


Diagnostic Accuracy of the Panbio SARS-CoV-2 Antigen Rapid Test Compared with Rt-Pcr Testing of Nasopharyngeal Samples in the Pediatric Population.

Villaverde S, et al. J Pediatr. 2021 Jan 20:S0022-3476(21)00034-2


Gestational age at birth and child special educational needs: a UK representative birth cohort study.

Alterman N, et al. Arch Dis Child. 2021 Jan 22:archdischild-2020-320213.


Body composition monitoring in children and adolescents: reproducibility and reference values.

Van Eyck A, et al. Eur J Pediatr. 2021 Jan 22


Comparison of Manual and Automated Sepsis Screening Tools in a Pediatric Emergency Department.

Eisenberg M, et al. Pediatrics. 2021 Jan 20:e2020022590.


Home phototherapy for hyperbilirubinemia in term neonates-an unblinded multicentre randomized controlled trial.

Pettersson M, et al. Eur J Pediatr. 2021 Jan 19


Romantic Relationships in Transgender Adolescents: A Qualitative Study.

Araya AC, et al. Pediatrics. 2021 Jan 19:e2020007906.


Maternal caffeine intake during pregnancy and risk of food allergy in young Japanese children.

Tanaka K, et al. J Paediatr Child Health. 2021 Jan 19.


More Evidence Linking Autoimmune Diseases to Attention-Deficit/Hyperactivity Disorder.

Dalsgaard S. JAMA Pediatr. 2021 Jan 19:e205502


Association of Maternal Autoimmune Disease With Attention-Deficit/Hyperactivity Disorder in Children.

Nielsen TC, et al. JAMA Pediatr. 2021 Jan 19:e205487


Do children with solitary or hypofunctioning kidney have the same prevalence for masked hypertension?

Yel S, et al. Pediatr Nephrol. 2021 Jan 18


Association of Bacteremia with Vaccination Status in Children Aged 2 to 36 Months.

Dunnick J, et al. J Pediatr. 2021 Jan 13:S0022-3476(21)00009-3


CONservative TReatment of Appendicitis in Children: a randomised controlled feasibility Trial (CONTRACT).

Hall NJ, et al. Arch Dis Child. 2021 Jan 13:archdischild-2020-320746


Use of E-cigarettes and Other Tobacco Products and Progression to Daily Cigarette Smoking.

Pierce JP, et al. Pediatrics. 2021 Jan 11:e2020025122.


Oropharyngeal Carriage of Kingella kingae and Transient Synovitis of the Hip in Young Children: A Case-Control Study.

Gravel J, et al. Pediatr Infect Dis J. 2021 Jan 7;Publish Ahead of Print


Caesarean delivery is associated with an absolute increase in the prevalence of overweight in the offspring: The SENDO project.

Moreno-Galarraga L, et al. J Paediatr Child Health. 2021 Jan 11. doi: 10.1111/jpc.15328.


Vestibular, Gaze, and Balance Disorders in Asymptomatic Congenital Cytomegalovirus Infection.

Pinninti S, et al. Pediatrics. 2021 Jan 8:e20193945


Vestibular Disorders in Congenital Cytomegalovirus: A Balancing Act.

Demmler-Harrison GJ. Pediatrics. 2021 Jan 8:e2020043778.


What is the risk of missing orbital cellulitis in children?

Ibrahim LF, et al. Arch Dis Child. 2021 Jan 8:archdischild-2020-320590.


Rectal Biopsy Technique for the Diagnosis of Hirschsprung Disease in Children: A Systematic Review and Meta-Analysis.

Comes GT, et al. J Pediatr Gastroenterol Nutr. 2021 Jan 6;Publish Ahead of Print


Lower HbA1c targets are associated with better metabolic control.

Van Loocke M, et al. Eur J Pediatr. 2021 Jan 7


The impact of COVID-19 on a tertiary care pediatric emergency department.

Liguoro I, et al. Eur J Pediatr. 2021 Jan 7:1-8.


Mental Health Disorders in Children With Congenital Heart Disease.

Gonzalez VJ, et al. Pediatrics. 2021 Jan 4:e20201693


Translation of a Host Blood RNA Signature Distinguishing Bacterial From Viral Infection Into a Platform Suitable for Development as a Point-of-Care Test.

Pennisi I, et al. JAMA Pediatr. 2021 Jan 4:e205227


Neutropenia in Children Treated With Ketogenic Diet Therapy.

Munro K, et al. J Child Neurol. 2021 Jan 4:883073820984067


From rigid to flexible bronchoscopy: a tertiary center experience in removal of inhaled foreign bodies in children.

Golan-Tripto I, et al. Eur J Pediatr. 2021 Jan 3


‘Lip-to-Tip’ study: comparison of three methods to determine optimal insertion length of endotracheal tube in neonates.

Priyadarshi M, et al. Eur J Pediatr. 2021 Jan 3.


Improving Toddlers’ Healthy Eating Habits and Self-regulation: A Randomized Controlled Trial.

Nix RL, et al. Pediatrics. 2021 Jan;147(1):e20193326


Association of Cesarean Delivery with Childhood Hospitalization for Infections Before 13 Years of Age.

Auger N, et al. J Pediatr. 2021 Jan 6:S0022-3476(20)31546-8.


Early Physical Abuse and Adult Outcomes.

Lansford JE, et al. Pediatrics. 2021 Jan;147(1):e20200873


Child Maltreatment and Mortality in Young Adults.

Segal L, et al. Pediatrics. 2021 Jan;147(1):e2020023416.


Risk of Electrolyte Disorders in Acutely Ill Children Receiving Commercially Available Plasmalike Isotonic Fluids: A Randomized Clinical Trial.

Lehtiranta S, et al. JAMA Pediatr. 2021 Jan 1;175(1):28-35


Vaginal Transmission of Cancer from Mothers with Cervical Cancer to Infants.

Arakawa A, et al. N Engl J Med. 2021 Jan 7;384(1):42-50


Stillbirths During the COVID-19 Pandemic in England, April-June 2020.

Stowe J, et al. JAMA. 2021 Jan 5;325(1):86-87


Changes in Preterm Birth Phenotypes and Stillbirth at 2 Philadelphia Hospitals During the SARS-CoV-2 Pandemic, March-June 2020.

Handley SC, et al. JAMA. 2021 Jan 5;325(1):87-89




The use of diagnostic tools for pediatric AKI: applying the current evidence to the bedside.

Fuhrman D. Pediatr Nephrol. 2021 Jan 25.


Is ultrasonography mandatory in all children at their first febrile urinary tract infection?

Pennesi M, et al. Pediatr Nephrol. 2021 Jan 22.


Morphine or hydromorphone: which should be preferred? A systematic review.

Spénard S, et al. Arch Dis Child. 2021 Jan 18:archdischild-2020-319059.


Fetal alcohol spectrum disorders: an overview of current evidence and activities in the UK.

Schölin L, et al. Arch Dis Child. 2021 Jan 13:archdischild-2020-320435.


Systematic review with meta-analysis: Probiotics for treating acute diarrhoea in children with dehydration.

Wu HL, et al. J Paediatr Child Health. 2021 Jan 7


Machine Learning for Child and Adolescent Health: A Systematic Review.

Hoodbhoy Z, et al. Pediatrics. 2021 Jan;147(1):e2020011833.




When Pneumonia Is Not Resolved with Antibiotics: The Incomplete Border Sign.

Pérez-Torres Lobato MR, et al. J Pediatr. 2021 Jan 22:S0022-3476(21)00076-7


Isolated forehead swelling.

Nistico D, et al. J Pediatr. 2021 Jan 11:S0022-3476(21)00004-4


Case 2-2021: A 26-Year-Old Pregnant Woman with Ventricular Tachycardia and Shock.

Scott NS, et al. N Engl J Med. 2021 Jan 21;384(3):272-282.


Why the Maternal Medication List Matters: Neonatal Toxicity From Combined Serotonergic Exposures.


Brajcich MR, et al. Pediatrics. 2021 Jan 27:e20192250.