The part with the review articles contains interesting contributions about: acute kidney injury, neuroprotection for neonatal HIE, asthma exacerbations, paediatric concussions, COVID vaccines…

In the part with the clinical studies you may find the answer to the following questions:

• Does rapid viral testing have an effect on antibiotic prescription?
• Is there a new and better way to evaluate febrile infants?
• Is procalcitonin a good biomarker for late onset neonatal sepsis?
• Why are children with asthma bullied?
• How long should children with Kawasaki disease without coronary aneurysms be followed up?
• Does a higher APGAR score correlate with lower mortality in very preterm infants?
• Can preschool children still recognise emotions despite a facemask?
• How well do paediatricians adhere to guidelines for hypertension?
• Are ‘nose and throat’ swabs more painful than ‘anterior nasal’ swabs in children?
• Is COVID-19 vaccination-associated myocarditis common in adolescence?

Selection for the Pediatric Journal Club: DECEMBER 2021.

REVIEWS AND OPINION ARTICLES

Acute kidney injury in pediatrics: an overview focusing on pathophysiology.

Ruas AFL, et al. Pediatr Nephrol. 2021 Nov 30.

Ethical advice in paediatric care.

Brierley J, et al. Arch Dis Child. 2021 Nov 29:archdischild-2021-322671.

New possibilities for neuroprotection in neonatal hypoxic-ischemic encephalopathy.

Victor S, et al. Eur J Pediatr. 2021 Nov 24.

Managing an acute asthma exacerbation in children.

Trottier ED, et al. Paediatr Child Health. 2021 Nov 11;26(7):438-439.

Diagnosing and managing paediatric concussion: Key recommendations for general paediatricians and family doctors.

Dawson J, et al. Paediatr Child Health. 2021 May 20;26(7):402-407.

Update on the management of a newborn with a suspected difference of sex development.

Lucas-Herald AK, et al. Arch Dis Child. 2021 Nov 12:archdischild-2020-320872.

COVID-19 Vaccines in Children and Adolescents.

Committee on Infectious Diseases. Pediatrics. 2021 Nov 5:e2021054332.

Should children be vaccinated against COVID-19?

Zimmermann P, et al. Arch Dis Child. 2021 Nov 3:archdischild-2021-323040.

Clinical management of complex motor stereotypies.

Bhatoa RS, et al. Arch Dis Child. 2021 Nov 1:archdischild-2021-322624.

Biologics for Asthma and Allergic Skin Diseases in Children.

De Keyser HH, et al. Pediatrics. 2021 Nov;148(5):e2021054270.

ORIGINAL CLINICAL STUDIES

Rapid Viral Testing and Antibiotic Prescription in Febrile Children With Respiratory Symptoms Visiting Emergency Departments in Europe.

Tan CD, et al. Pediatr Infect Dis J. 2021 Nov 30.

Varying international practices regarding the evaluation of febrile young infants.

Umana E, et al. Arch Dis Child. 2021 Nov;106(11):1037-1038.

Impact of the Step-by-Step on febrile infants.

Gomez B, et al. Arch Dis Child. 2021 Nov;106(11):1047-1049.

Antimicrobial Susceptibility Profiles Among Neonatal Early-onset Sepsis Pathogens.

Flannery DD, et al. Pediatr Infect Dis J. 2021 Nov 30.

Procalcitonin is a prognosis biomarker in very preterm neonates with late onset sepsis: a pilot study.

Ruetsch V, et al. Eur J Pediatr. 2021 Nov 30.

Why are children with asthma bullied? A risk factor analysis.

Charles R, et al. Arch Dis Child. 2021 Nov 30:archdischild-2021-321641.

Instructional guides for filming infant movements at home are effective for the General Movements Assessment.

Kwong AKL, et al. J Paediatr Child Health. 2021 Nov 30.

Placental Findings among Infants with Hypoxic-Ischemic Encephalopathy (HIE): The Importance of the Comparison Group.

Bingham A, et al. J Pediatr. 2021 Nov 27:S0022-3476(21)01160-4.

Human Papillomavirus Vaccination and Trends in Cervical Cancer Incidence and Mortality in the US.

Tabibi T, et al. JAMA Pediatr. 2021 Nov 29.

Postnatal Cytomegalovirus Infection of Preterm and Very-low-birth-weight Infants Through Maternal Breast Milk: Does It Matter?

Bimboese P, et al. Pediatr Infect Dis J. 2021 Nov 29.

Evaluation of trends in Bronchopulmonary Dysplasia and Respiratory Support Practice for Very Low Birth Weight Infants: A Population-Based Cohort Study.

Lee SM, et al. J Pediatr. 2021 Nov 24:S0022-3476(21)01147-1.

Neonatal Group B Streptococcal Meningitis: Predictors for Poor Neurologic Outcome at 18 Months.

Fister P, et al. J Child Neurol. 2021 Nov 24:8830738211053128.

Acceptability of different oral dosage forms in paediatric patients in hospital setting.

Pokharkar V, et al. Arch Dis Child. 2021 Nov 19:archdischild-2021-322604.

Follow-up duration of echocardiography in patients with Kawasaki disease with no initial coronary aneurysms.

Wang Q, et al. J Pediatr. 2021 Nov 16:S0022-3476(21)01094-5.

Five-minute Apgar score and outcomes in neonates of 24-28 weeks’ gestation.

Shah PS, et al. Arch Dis Child Fetal Neonatal Ed. 2021 Nov 15:fetalneonatal-2021-322230.

State Laws Permitting Adolescent Consent to Human Papillomavirus Vaccination and Rates of Immunization.

Torres AR, et al. JAMA Pediatr. 2021 Nov 15:e214591.

The Role of Face Masks in the Recognition of Emotions by Preschool Children.

Schneider J, et al. JAMA Pediatr. 2021 Nov 15:e214556.

Pediatric Acute Stroke Protocols in the United States and Canada.

Harrar DB, et al. J Pediatr. 2021 Nov 11:S0022-3476(21)01048-9.

Non-Invasive Respiratory Severity Indices Predict Adverse Outcomes in Bronchopulmonary Dysplasia.

Kielt MJ, et al. J Pediatr. 2021 Nov 10:S0022-3476(21)01080-5.

Pediatrician Adherence to Guidelines for Diagnosis and Management of High Blood Pressure.

Rea CJ, et al. J Pediatr. 2021 Nov 10:S0022-3476(21)01073-8.

Paediatric enteric fever in Brussels: a case series over 16 years.

Selimaj Kontoni V, et al. Eur J Pediatr. 2021 Nov 11.

Noninferiority and Safety of Nadolol vs Propranolol in Infants With Infantile Hemangioma: A Randomized Clinical Trial.

Pope E, et al. JAMA Pediatr. 2021 Nov 8:e214565.

Comparison of the pain experienced with anterior nasal swabs and nose and throat swabs in children.

Harwood R, et al. Arch Dis Child. 2021 Nov 2:archdischild-2021-321708.

Preventing Home Medication Administration Errors.

Yin HS, et al. Pediatrics. 2021 Nov 1:e2021054666.

Trends in Management of Simple Febrile Seizures at US Children’s Hospitals.

Raghavan VR, et al. Pediatrics. 2021 Nov;148(5):e2021051517.

Exercise Intervention for Academic Achievement Among Children: A Randomized Controlled Trial.

Takehara K, et al. Pediatrics. 2021 Nov;148(5):e2021052808.

Preseptal Versus Orbital Cellulitis in Children: An Observational Study.

Miranda-Barrios J, et al. Pediatr Infect Dis J. 2021 Nov 1;40(11):969-974

Effect of Screen Time on Recovery From Concussion: A Randomized Clinical Trial.

Macnow T, et al. JAMA Pediatr. 2021 Nov 1;175(11):1124-1131.

Health-related Quality of Life After Childhood Bacterial Meningitis.

Rugemalira E, et al. Pediatr Infect Dis J. 2021 Nov 1;40(11):987-992.

Myopericarditis After the Pfizer Messenger Ribonucleic Acid Coronavirus Disease Vaccine in Adolescents.

Schauer J, et al. J Pediatr. 2021 Nov;238:317-320.

COVID-19 Vaccination-Associated Myocarditis in Adolescents.

Jain SS, et al. Pediatrics. 2021 Nov;148(5):e2021053427.

The Rise of Eating Disorders During COVID-19 and the Impact on Treatment.

Reed J, et al. J Am Acad Child Adolesc Psychiatry. 2021 Nov 10:S0890-8567(21)01976-6.

Impact of the Coronavirus Pandemic on Anorexia Nervosa and Atypical Anorexia Nervosa Presentations.

Heeney C, et al. J Paediatr Child Health. 2021 Nov 8.

GUIDELINES AND BEST EVIDENCE

Early-life gut microbiota and neurodevelopment in preterm infants: any role for Bifidobacterium?

Beghetti I, et al. Eur J Pediatr. 2021 Nov 29.

Torticollis in childhood-a practical guide for initial assessment.

Ben Zvi I, et al. Eur J Pediatr. 2021 Nov 12.

Experiences With Genetic Counseling, Testing, and Diagnosis Among Adolescents With a Genetic Condition: A Scoping Review.

Wainstein T, et al. JAMA Pediatr. 2021 Nov 22.

CASE REPORTS

Severe hyponatraemia secondary to psychogenic polydipsia in a patient with anorexia nervosa.

Che Mokhtar M, et al. J Paediatr Child Health. 2021 Nov 18.

A Circular rash in a teenager.

Shih AF, et al. J Pediatr. 2021 Nov 14:S0022-3476(21)01083-0.

An 11-month-old boy with uvulo-palatoglossal junctional ulcers.

Miyamoto M, et al. Paediatr Child Health. 2021 Aug 3;26(7):392-393.

Amoxicillin Adverse Cutaneous Reaction Versus Post Streptococcal Vasculitis: Lymphocyte Transformation Test Solved the Question.

Liccioli G, et al. Pediatr Infect Dis J. 2021 Nov 30.The part with the review articles contains interesting contributions about: acute kidney injury, neuroprotection for neonatal HIE, asthma exacerbations, paediatric concussions, COVID vaccines…

In the part with the clinical studies you may find the answer to the following questions:

• Does rapid viral testing have an effect on antibiotic prescription?
• Is there a new and better way to evaluate febrile infants?
• Is procalcitonin a good biomarker for late onset neonatal sepsis?
• Why are children with asthma bullied?
• How long should children with Kawasaki disease without coronary aneurysms be followed up?
• Does a higher APGAR score correlate with lower mortality in very preterm infants?
• Can preschool children still recognise emotions despite a facemask?
• How well do paediatricians adhere to guidelines for hypertension?
• Are ‘nose and throat’ swabs more painful than ‘anterior nasal’ swabs in children?
• Is COVID-19 vaccination-associated myocarditis common in adolescence?

Selection for the Pediatric Journal Club: DECEMBER 2021.

REVIEWS AND OPINION ARTICLES

Acute kidney injury in pediatrics: an overview focusing on pathophysiology.

Ruas AFL, et al. Pediatr Nephrol. 2021 Nov 30.

Ethical advice in paediatric care.

Brierley J, et al. Arch Dis Child. 2021 Nov 29:archdischild-2021-322671.

New possibilities for neuroprotection in neonatal hypoxic-ischemic encephalopathy.

Victor S, et al. Eur J Pediatr. 2021 Nov 24.

Managing an acute asthma exacerbation in children.

Trottier ED, et al. Paediatr Child Health. 2021 Nov 11;26(7):438-439.

Diagnosing and managing paediatric concussion: Key recommendations for general paediatricians and family doctors.

Dawson J, et al. Paediatr Child Health. 2021 May 20;26(7):402-407.

Update on the management of a newborn with a suspected difference of sex development.

Lucas-Herald AK, et al. Arch Dis Child. 2021 Nov 12:archdischild-2020-320872.

COVID-19 Vaccines in Children and Adolescents.

Committee on Infectious Diseases. Pediatrics. 2021 Nov 5:e2021054332.

Should children be vaccinated against COVID-19?

Zimmermann P, et al. Arch Dis Child. 2021 Nov 3:archdischild-2021-323040.

Clinical management of complex motor stereotypies.

Bhatoa RS, et al. Arch Dis Child. 2021 Nov 1:archdischild-2021-322624.

Biologics for Asthma and Allergic Skin Diseases in Children.

De Keyser HH, et al. Pediatrics. 2021 Nov;148(5):e2021054270.

ORIGINAL CLINICAL STUDIES

Rapid Viral Testing and Antibiotic Prescription in Febrile Children With Respiratory Symptoms Visiting Emergency Departments in Europe.

Tan CD, et al. Pediatr Infect Dis J. 2021 Nov 30.

Varying international practices regarding the evaluation of febrile young infants.

Umana E, et al. Arch Dis Child. 2021 Nov;106(11):1037-1038.

Impact of the Step-by-Step on febrile infants.

Gomez B, et al. Arch Dis Child. 2021 Nov;106(11):1047-1049.

Antimicrobial Susceptibility Profiles Among Neonatal Early-onset Sepsis Pathogens.

Flannery DD, et al. Pediatr Infect Dis J. 2021 Nov 30.

Procalcitonin is a prognosis biomarker in very preterm neonates with late onset sepsis: a pilot study.

Ruetsch V, et al. Eur J Pediatr. 2021 Nov 30.

Why are children with asthma bullied? A risk factor analysis.

Charles R, et al. Arch Dis Child. 2021 Nov 30:archdischild-2021-321641.

Instructional guides for filming infant movements at home are effective for the General Movements Assessment.

Kwong AKL, et al. J Paediatr Child Health. 2021 Nov 30.

Placental Findings among Infants with Hypoxic-Ischemic Encephalopathy (HIE): The Importance of the Comparison Group.

Bingham A, et al. J Pediatr. 2021 Nov 27:S0022-3476(21)01160-4.

Human Papillomavirus Vaccination and Trends in Cervical Cancer Incidence and Mortality in the US.

Tabibi T, et al. JAMA Pediatr. 2021 Nov 29.

Postnatal Cytomegalovirus Infection of Preterm and Very-low-birth-weight Infants Through Maternal Breast Milk: Does It Matter?

Bimboese P, et al. Pediatr Infect Dis J. 2021 Nov 29.

Evaluation of trends in Bronchopulmonary Dysplasia and Respiratory Support Practice for Very Low Birth Weight Infants: A Population-Based Cohort Study.

Lee SM, et al. J Pediatr. 2021 Nov 24:S0022-3476(21)01147-1.

Neonatal Group B Streptococcal Meningitis: Predictors for Poor Neurologic Outcome at 18 Months.

Fister P, et al. J Child Neurol. 2021 Nov 24:8830738211053128.

Acceptability of different oral dosage forms in paediatric patients in hospital setting.

Pokharkar V, et al. Arch Dis Child. 2021 Nov 19:archdischild-2021-322604.

Follow-up duration of echocardiography in patients with Kawasaki disease with no initial coronary aneurysms.

Wang Q, et al. J Pediatr. 2021 Nov 16:S0022-3476(21)01094-5.

Five-minute Apgar score and outcomes in neonates of 24-28 weeks’ gestation.

Shah PS, et al. Arch Dis Child Fetal Neonatal Ed. 2021 Nov 15:fetalneonatal-2021-322230.

State Laws Permitting Adolescent Consent to Human Papillomavirus Vaccination and Rates of Immunization.

Torres AR, et al. JAMA Pediatr. 2021 Nov 15:e214591.

The Role of Face Masks in the Recognition of Emotions by Preschool Children.

Schneider J, et al. JAMA Pediatr. 2021 Nov 15:e214556.

Pediatric Acute Stroke Protocols in the United States and Canada.

Harrar DB, et al. J Pediatr. 2021 Nov 11:S0022-3476(21)01048-9.

Non-Invasive Respiratory Severity Indices Predict Adverse Outcomes in Bronchopulmonary Dysplasia.

Kielt MJ, et al. J Pediatr. 2021 Nov 10:S0022-3476(21)01080-5.

Pediatrician Adherence to Guidelines for Diagnosis and Management of High Blood Pressure.

Rea CJ, et al. J Pediatr. 2021 Nov 10:S0022-3476(21)01073-8.

Paediatric enteric fever in Brussels: a case series over 16 years.

Selimaj Kontoni V, et al. Eur J Pediatr. 2021 Nov 11.

Noninferiority and Safety of Nadolol vs Propranolol in Infants With Infantile Hemangioma: A Randomized Clinical Trial.

Pope E, et al. JAMA Pediatr. 2021 Nov 8:e214565.

Comparison of the pain experienced with anterior nasal swabs and nose and throat swabs in children.

Harwood R, et al. Arch Dis Child. 2021 Nov 2:archdischild-2021-321708.

Preventing Home Medication Administration Errors.

Yin HS, et al. Pediatrics. 2021 Nov 1:e2021054666.

Trends in Management of Simple Febrile Seizures at US Children’s Hospitals.

Raghavan VR, et al. Pediatrics. 2021 Nov;148(5):e2021051517.

Exercise Intervention for Academic Achievement Among Children: A Randomized Controlled Trial.

Takehara K, et al. Pediatrics. 2021 Nov;148(5):e2021052808.

Preseptal Versus Orbital Cellulitis in Children: An Observational Study.

Miranda-Barrios J, et al. Pediatr Infect Dis J. 2021 Nov 1;40(11):969-974

Effect of Screen Time on Recovery From Concussion: A Randomized Clinical Trial.

Macnow T, et al. JAMA Pediatr. 2021 Nov 1;175(11):1124-1131.

Health-related Quality of Life After Childhood Bacterial Meningitis.

Rugemalira E, et al. Pediatr Infect Dis J. 2021 Nov 1;40(11):987-992.

Myopericarditis After the Pfizer Messenger Ribonucleic Acid Coronavirus Disease Vaccine in Adolescents.

Schauer J, et al. J Pediatr. 2021 Nov;238:317-320.

COVID-19 Vaccination-Associated Myocarditis in Adolescents.

Jain SS, et al. Pediatrics. 2021 Nov;148(5):e2021053427.

The Rise of Eating Disorders During COVID-19 and the Impact on Treatment.

Reed J, et al. J Am Acad Child Adolesc Psychiatry. 2021 Nov 10:S0890-8567(21)01976-6.

Impact of the Coronavirus Pandemic on Anorexia Nervosa and Atypical Anorexia Nervosa Presentations.

Heeney C, et al. J Paediatr Child Health. 2021 Nov 8.

GUIDELINES AND BEST EVIDENCE

Early-life gut microbiota and neurodevelopment in preterm infants: any role for Bifidobacterium?

Beghetti I, et al. Eur J Pediatr. 2021 Nov 29.

Torticollis in childhood-a practical guide for initial assessment.

Ben Zvi I, et al. Eur J Pediatr. 2021 Nov 12.

Experiences With Genetic Counseling, Testing, and Diagnosis Among Adolescents With a Genetic Condition: A Scoping Review.

Wainstein T, et al. JAMA Pediatr. 2021 Nov 22.

CASE REPORTS

Severe hyponatraemia secondary to psychogenic polydipsia in a patient with anorexia nervosa.

Che Mokhtar M, et al. J Paediatr Child Health. 2021 Nov 18.

A Circular rash in a teenager.

Shih AF, et al. J Pediatr. 2021 Nov 14:S0022-3476(21)01083-0.

An 11-month-old boy with uvulo-palatoglossal junctional ulcers.

Miyamoto M, et al. Paediatr Child Health. 2021 Aug 3;26(7):392-393.

Amoxicillin Adverse Cutaneous Reaction Versus Post Streptococcal Vasculitis: Lymphocyte Transformation Test Solved the Question.

Liccioli G, et al. Pediatr Infect Dis J. 2021 Nov 30.