The reviews discuss topics such as: neonatal airway management, optimal administration of bronchodilators, renovascular hypertension,…

In the part with the clinical studies, you may find the answer to the following questions:

• What is the threshold for treatment in prematurity according to neonatal staff? 22 of 23 weeks of gestation?
• Does the administration of colostrum reduce mortality in very preterms?
• Is exclusive breastfeeding associated with better physical growth and cognitive development?
• Can suffocation explain 20 or 50% of sudden unexpected infant deaths?
• Does a prone position improve cerebral oxygenation in preterms?
• Are we becoming better at predicting the need for phototherapy?
• Is maternal fever a reliable predictor of neonatal sepsis?
• Is fecal calprotectin a useful marker for Small Bowel Crohn’s Disease?
• Is a ‘non-biopsy approach’ reliable to diagnose celiac disease?
• Is celiac disease testing necessary in functional abdominal disorders?
• Could automated analysis of chest X-rays detect early bronchiectasis in children?
• Can clinicians discriminate children with pneumonia who develop severe complications from those who do not? L
• How strong is the evidence for our current bronchiolitis treatments?
• Is the use of PPI associated with a risk of  asthma?
• Is pseudotumor cerebri the only risk factor for post-LP headache in children?
• Is pertussis vaccination in pregnancy associated with adverse health outcomes in early childhood?
• What is the “Rule of 7’s” in the context of Lyme meningitis?
• Do rapid diagnostic methods improve antibiotic prescribing in pediatric bacteraemia?

SELECTION OF ARTICLES FOR THE PEDIATRIC JOURNAL CLUB: MAY 2021

REVIEWS AND OPINION ARTICLES

Safe emergency neonatal airway management: current challenges and potential approaches.

O’Shea JE, et al. Arch Dis Child Fetal Neonatal Ed. 2021 Apr 21:fetalneonatal-2020-319398.

Optimal administration of bronchodilators with valved holding chambers in preschool children: a review of literature.

Csonka P, et al. Eur J Pediatr. 2021 Apr 20:1-9.

Maltreatment of Children With Disabilities.

Legano LA, et al. Pediatrics. 2021 Apr 19:e2021050920.

Renovascular hypertension in pediatric patients: update on diagnosis and management.

de Oliveira Campos JL, et al. Pediatr Nephrol. 2021 Apr 13.

Adolescent Consent for Human Papillomavirus Vaccine: Ethical, Legal, and Practical Considerations.

Zimet GD, et al. J Pediatr. 2021 Apr;231:24-30.

ORIGINAL CLINICAL STUDIES

Viability and thresholds for treatment of extremely preterm infants: survey of UK neonatal professionals.

Di Stefano LM, et al. Arch Dis Child Fetal Neonatal Ed. 2021 Apr 29:fetalneonatal-2020-321273.

Ethical issues in treatment of babies born at 22 weeks of gestation.

Lantos JD. Arch Dis Child. 2021 Apr 14:archdischild-2020-320871.

Does oropharyngeal administration of colostrum reduce morbidity and mortality in very preterm infants? A randomised parallel-group controlled trial.

Aggarwal R, et al. J Paediatr Child Health. 2021 Apr 28.

Breastfeeding, Physical Growth, and Cognitive Development.

Wallenborn JT, et al. Pediatrics. 2021 Apr 22:e2020008029.

Explaining Sudden Unexpected Infant Deaths, 2011-2017.

Parks SE, et al. Pediatrics. 2021 Apr 27:e2020035873.

Cerebral Oxygenation and Perfusion When Positioning Preterm Infants: Clinical Implications.

Jani PR, et al. J Pediatr. 2021 Apr 12:S0022-3476(21)00329-2.

Predicting the Need for Phototherapy After Discharge.

Kuzniewicz MW, et al. Pediatrics. 2021 Apr 26:e2020019778.

Simplifying Hyperbilirubinemia Risk Estimation.

Kair LR, et al. Pediatrics. 2021 Apr 26:e2020046284.

Rates and Determinants of Mother’s Own Milk Feeding in Infants Born Very Preterm.

Dharel D, et al. J Pediatr. 2021 Apr 23:S0022-3476(21)00388-7.

Is peripartum maternal fever alone a reliable predictor of neonatal sepsis? A single-centre, retrospective cohort study.

Gupta S, et al. J Paediatr Child Health. 2021 Apr 22.

Neonatal hyperglycaemia is associated with worse neurodevelopmental outcomes in extremely preterm infants.

Zamir I, et al. Arch Dis Child Fetal Neonatal Ed. 2021 Apr 16:fetalneonatal-2020-319926.

Effect of Enteral Lipid Supplement on Severe Retinopathy of Prematurity: A Randomized Clinical Trial.

Hellström A, et al. JAMA Pediatr. 2021 Apr 1;175(4):359-367.

Evaluation of parameters associated with growth retardation in children with coeliac disease.

Taskin DG, et al. J Paediatr Child Health. 2021 Apr 28.

Is Fecal Calprotectin a Useful Marker for Small Bowel Crohn’s Disease?

D’Arcangelo G, et al. J Pediatr Gastroenterol Nutr. 2021 Apr 14.

Efficient implementation of the ‘non-biopsy approach’ for the diagnosis of childhood celiac disease in the Netherlands: a national prospective evaluation 2010-2013.

Meijer CR, et al. Eur J Pediatr. 2021 Apr 15.

Is Celiac Disease Testing Necessary in Functional Abdominal Disorders? A Study in Predominantly Latino Children.

Falcon AC, et al. J Pediatr Gastroenterol Nutr. 2021 Apr 1;72(4):542-545.

Could automated analysis of chest X-rays detect early bronchiectasis in children?

Clark AR, et al. Eur J Pediatr. 2021 Apr 28:1-9.

Clinician Gestalt in Managing Pediatric Pneumonia: Can We Predict the Future?

Fatemi Y, Bell LM.Pediatrics. 2021 Apr 26:e2020048637.

Predictive Value of Clinician “Gestalt” in Pediatric Community-Acquired Pneumonia.

Gao HM, et al. Pediatrics. 2021 Apr 26:e2020041582.

Survival outcomes of in-hospital cardiac arrest in pediatric patients in the USA.

Hamzah M, et al. Eur J Pediatr. 2021 Apr 26.

Pneumococcal Conjugated Vaccines Decreased Acute Otitis Media Burden: A Population-Based Study in Israel.

Marom T, et al. J Pediatr. 2021 Apr 21:S0022-3476(21)00351-6.

Comparative Efficacy of Bronchiolitis Interventions in Acute Care: A Network Meta-analysis.

Elliott SA, et al. Pediatrics. 2021 Apr 23:e2020040816.

“Don’t Just Do Something, Stand There”: Embracing Deimplementation of Bronchiolitis Therapeutics.

Lipshaw MJ, et al. Pediatrics. 2021 Apr 23:e2020048645.

Burden of respiratory syncytial virus bronchiolitis on the Dutch pediatric intensive care units.

Linssen RS, et al. Eur J Pediatr. 2021 Apr 23.

Association Between Proton Pump Inhibitor Use and Risk of Asthma in Children.

Wang YH, et al. JAMA Pediatr. 2021 Apr 1;175(4):394-403.

Strikingly Decreased Community-acquired Pneumonia Admissions in Children Despite Open Schools and Day-care Facilities in Switzerland.

Kohns Vasconcelos M, et al. Pediatr Infect Dis J. 2021 Apr 1;40(4):e171-e172.

Assessment of Peak Inspiratory Flow in Young Infants with Acute Viral Bronchiolitis: Physiological Basis for Initial Flow Setting in Patients Supported with High-Flow Nasal Cannula.

Milési C, et al. J Pediatr. 2021 Apr;231:239-245.e1.

Examining differences in parents’ perceptions of children’s physical activity versus screen time guidelines and behaviours.

Jarvis JW, et al. J Paediatr Child Health. 2021 Apr 23.

Factors Predisposing to Post Dural Puncture Headache in Children.

Bandatmakur M, et al. J Child Neurol. 2021 Apr 21:8830738211007699.

Ultrasound for the diagnosis of malrotation and volvulus in children and adolescents: a systematic review and meta-analysis.

Nguyen HN, et al. Arch Dis Child. 2021 Apr 20:archdischild-2020-321082.

Health Outcomes in Young Children Following Pertussis Vaccination During Pregnancy.

Laverty M, et al. Pediatrics. 2021 Apr 19:e2020042507.

Clinical prediction of iron deficiency at age 2: a national cross-sectional study in France.

Guivarch C, et al. J Pediatr. 2021 Apr 6:S0022-3476(21)00321-8.

Subconcussive Head Impacts and Neurocognitive Function Over 3 Seasons of Youth Football.

Rose SC, et al. J Child Neurol. 2021 Apr 9:8830738211004490.

Validation of the Rule of 7’s for Identifying Children at Low-risk for Lyme Meningitis.

Garro A, et al. Pediatr Infect Dis J. 2021 Apr 1;40(4):306-309.

Kawasaki Disease Shock Syndrome Versus Septic Shock: Early Differentiating Features Despite Overlapping Clinical Profiles.

Power A, et al. J Pediatr. 2021 Apr;231:162-167.

Do rapid diagnostic methods improve antibiotic prescribing in paediatric bacteraemia?

Faugno AK, et al. J Paediatr Child Health. 2021 Apr;57(4):574-580.

Perinatal COVID-19: review of current evidence and practical approach towards prevention and management.

Vardhelli V, et al. Eur J Pediatr. 2021 Apr;180(4):1009-1031.

COVID-19 and Pediatric Ingestions.

Lelak KA, et al. Pediatrics. 2021 Apr 27:e2021051001.

Compassionate Use of Remdesivir in Children With Severe COVID-19.

Goldman DL, et al. Pediatrics. 2021 Apr 21:e2020047803.

Compassionate use of remdesivir in children with COVID-19.

Méndez-Echevarría A, et al. Eur J Pediatr. 2021 Apr;180(4):1317-1322.

GUIDELINES AND BEST EVIDENCE

Association of Clinical Guidelines and Decision Support with CT use in Pediatric Mild Traumatic Brain Injury.

Marin JR, et al. J Pediatr. 2021 Apr 21:S0022-3476(21)00352-8.

Cognitive Behavioral Therapy for Autism Spectrum Disorders: A Systematic Review.

Wang X, et al. Pediatrics. 2021 Apr 22:e2020049880.

Prognostic Models Predicting Mortality in Preterm Infants: Systematic Review and Meta-analysis.

van Beek PE, et al. Pediatrics. 2021 Apr 20:e2020020461

Recovery from chronic fatigue syndrome: a systematic review-heterogeneity of definition limits study comparison.

Moore Y, et al. Arch Dis Child. 2021 Apr 12:archdischild-2020-320196.

Effectiveness of probiotics and synbiotics in reducing duration of acute infectious diarrhea in pediatric patients in developed countries: a systematic review and meta-analysis.

Vassilopoulou L, et al. Eur J Pediatr. 2021 Apr 6.

The Use of Fecal Calprotectin Testing in Paediatric Disorders: A Position Paper of the European Society for Paediatric Gastroenterology and Nutrition Gastroenterology Committee.

Koninckx CR, et al. J Pediatr Gastroenterol Nutr. 2021 Apr 1;72(4):617-640.

Rectal Biopsy Technique for the Diagnosis of Hirschsprung Disease in Children: A Systematic Review and Meta-Analysis.

Comes GT, et al. J Pediatr Gastroenterol Nutr. 2021 Apr 1;72(4):494-500.

Systematic Review: Nonverbal Learning Disability.

Fisher PW, et al. J Am Acad Child Adolesc Psychiatry. 2021 Apr 19:S0890-8567(21)00234-3.

CASE REPORTS

Vaping the Venom: Oral Cavity Cancer in a Young Adult With Extensive Electronic Cigarette Use.

Klawinski D, et al. Pediatrics. 2021 Apr 29:e2020022301.

Unilateral Facial Paralysis.

McHugh CI, et al. J Pediatr. 2021 Apr 21:S0022-3476(21)00358-9.

A Previously Healthy 18-Year-Old Male With Fever, Arrhythmia, and Shock.

Umapathi KK, et al. Pediatrics. 2021 Apr 13:e2020017624.

Tic Disorder in an 8-Year-old Boy.

Coppola C, et al. Pediatr Infect Dis J. 2021 Apr 1;40(4):382-384.

Interesting case of vasculitis or suspected child abuse: A fast evolving story.

Nagar S, et al. J Paediatr Child Health. 2021 Apr 19.